First off, do not go to Prison Colony expecting loot. The bosses don't drop any blues so the only loot you're going to get is a blue 'Ring of Corruption' from turning in Kill Zeno quest and a green bow from another quest.

That said, there are 9 quests in Prison Colony, of which 2 is taken deep inside (more on that later). The other quests are all taken in the Thunder River center camp and right at the entrance of Prison Colony. One of the quests taken at the entrance will lead you to Khesatta but no worries, there is no follow-up to this quest so you can go buy aoc Khesatta after you have finished Prison Colony.

So, basically, you should be going there for some pretty easy xp from the 9 quest turn-ins.

Tips and Tricks

- The Cannibals in Prison Colony hits exceptionally hard as compared to everything else in the instance, including the bosses. So be prepared for this with enough tankage and/or healers. Luckily, they are only found in a small corner of the instance.